One man was arrested and cannabis seized after police stopped a car in the Coalisland area.
A search was carried out on both the car and the four men.
Two of the men were dealt with for possession of a Class B drug.
Police want the public to be vigilant and to report any concerns or suspicious activity.
Man in 90s dies following Co Down road crash
Police to increase patrols after second incident of shots being fired in Belfast
Woman charged over theft of campaigner’s car ‘must stay out of Belfast’
Bluetongue restrictions in Northern Ireland will be relaxed from Friday
Conviction led to safeguarding review at Presbyterian Church